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Carla Mattos

Northeastern University, USA

Biography

Carla Mattos received her PhD at MIT and did Post-doctoral work at Harvard University and at Brandeis University. She is a recipient of the Boroughs Wellcome Fund New Investigator Award in the Pharmacological Sciences, the CAREER award from the NSF and the Presidential Early Career Award for Scientists and Engineers. She uses a combination of biophysical and biochemical approaches to study Ras structure, dynamics and allosteric connections to infer and test hypothesis associated with function. She is actively engaged in the Ras initiative at the NCI through her collaborations at the Frederick National Laboratory for Cancer Research.

Abstract

Abstract : Allosteric modulation of the Ras active site: From biochemistry to binding specificity