Cell and Gene Therapy

Track 22: Cell Therapy in Pulmonology

Depending on the level of inflation, the human lung's surface area ranges from 35 to 100 m2, enabling an efficient exchange of the oxygen required for oxidative metabolism.Toxins in the air as well as microorganisms and their by-products are exposed to this contact area. Despite these on-going assaults, the lung in healthy people is able to govern tissue plasticity required for injury repair as well as immunological reactions (upregulation and down-modulation of responses), allowing the maintenance of homeostasis. Although the causes of many lung disorders are yet unknown, their complicated pathophysiology is frequently linked to immune response dysregulation (such as chronic inflammation in chronic pulmonary disease) and abnormal lung tissue repair mechanisms (such as idiopathic pulmonary fibrosis).